R. Loch Macdonald, M.D., Ph.D.

Dr. R. Loch Macdonald has been the Co-Founder and Chief Scientific Officer of Edge Therapeutics, Inc. since its inception in 2008 and also serves on the company’s board of directors. Dr. Macdonald is a scientist, researcher and neurosurgeon and a recognized expert on brain hemorrhage, including delayed cerebral ischemia (DCI). For the past 20 years, his research interest has focused on improving patient outcome after brain hemorrhage, with a specific focus on developing a cure for cerebral vasospasm and DCI.

Since 2007, he has served as Keenan Endowed Chair, Head, Division of Neurosurgery at St. Michael’s Hospital and Professor of Neurosurgery at the University of Toronto. Dr. Macdonald has published numerous articles and authored multiple textbooks, including one of the definitive textbooks on cerebral vasospasm used in medical schools throughout the world and the American Heart / American Stroke Association Guidelines on the management of intracerebral hemorrhage. His publications have been cited thousands of times and he has spoken at many international conferences on the topic of cerebral vasospasm and DCI. Prior to St. Michael’s Hospital, he was Professor of Surgery and Radiation & Cellular Oncology at the University of Chicago Medical Center.

Dr. Macdonald completed medical school at the University of British Columbia, Vancouver, British Columbia, Canada and completed his Ph.D. in Experimental Surgery at the University of Alberta, Edmonton, Alberta, Canada. He completed his Neurosurgery residency at the University of Toronto, Toronto, Ontario, Canada.